| Autor: |
Ito, Yasuhiko, Otsuka, Nobuaki, Nagai, Kazue, Muranaka, Akira, Yoneda, Masaya, Terashima, Hideaki, Yanagimoto, Shinichi |
| Zdroj: |
European Journal of Nuclear Medicine; Jun1982, Vol. 7 Issue 6, p260-265, 6p |
| Abstrakt: |
Lymphoscintigraphy with SC injection of Ga-citrate was carried out on patients with lymph node metastasis and malignant lymphoma. The dose given at each injection site was about 200 μCi and scintigraphy was started about 5 min after injection. Metastatic lymph nodes and malignant lymphoma were successfully imaged. This positive delineation corresponded well to cold lesions detected by lymphoscintigraphy with Tc-rhenium colloid in metastatic lymph nodes. Hotter lesions in malignant lymphoma were scanned positively with Tc-rhenium colloid by this method. In in vitro studies, incorporation of Ga-citrate in HeLa S3 cells was about 4 times that in macrophages, when the incubation time was 1 h, while colloidal uptake by macrophages was 13 times that by HeLa S3 cells. The binding of Ga to transferrin in lymph and pinocytosis are suggested mechanisms of localization. A combination of colloid-and sc Ga-lymphoscintigraphy would be of value in the diagnosis of lymph node disease. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink