Enzymatic synthesis and characterization of N-(carboxymethyl)-L-ornithine and N-(carboxymethyl)-L-lysine.

Autor: Miller, S., Donkersloot, J., Thompson, J.
Zdroj: Amino Acids; Jun1994, Vol. 6 Issue 2, p189-198, 10p
Abstrakt: This report describes the enzyme-catalyzed synthesis, characterization, and chromatographic separation of N-(carboxymethyl)-L-lysine and N-(carboxymethyl)-L-ornithine. The two N-(carboxyalkyl)amino acids are formed via a reductive condensation between glyoxylate and the ε- or δ-amino groups of lysine and ornithine, respectively. Both reactions are catalyzed by the NADPH-dependent enzyme, N-(carboxyethyl)ornithine synthase [EC 1.5.1.24], found in some strains of the lactic acid bacterium Lactococcus lactis subsp. lactis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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