Site specificity of protein glycation.
| Autor: | Walton, D., Shilton, B. |
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| Zdroj: | Amino Acids; Jun1991, Vol. 1 Issue 2, p199-203, 5p |
| Abstrakt: | The rate of nonenzymatic glycation of a protein amino group is dependent upon a number of factors, such as the accessibility to glucose molecules in solution, and local acid-base catalysis of the rearrangement of the Schiff base that is formed initially. This is illustrated by a study of the site specificity of liver alcohol dehydrogenase, in which an attempt has been made to interpret the data in terms of the three-dimensional structure of the enzyme molecule. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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