Highly sensitive detection of beta-2 transferrin in rhinorrhea and otorrhea as a marker for cerebrospinal fluid (C.S.F.) leakage.

Autor:	Fransen, P., Sindic, C., Thauvoy, C., Laterre, C., Stroobandt, G.
Zdroj:	Acta Neurochirurgica; 1991, Vol. 109 Issue 3/4, p98-101, 4p
Abstrakt:	As beta-2 transferrin is almost specific to the cerebrospinal fluid, its detection in rhinorrhea or otorrhea fluids demonstrates the occurrence of CSF fistula. We describe a highly sensitive method based on immunoaffinity-mediated capillary blotting for the detection of this cathodic isoform of transferrin in minute amounts (3 μl) of rhinorrhea or otorrhea fluids. Application of this method in a series of 10 patients with CSF fistula is reported. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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