Determination of the optimum dose level of lipiodol in transcatheter arterial embolization of primary hepatocellular carcinoma based on retrospective multivariate analysis.

Autor: Nakao, Norio, Uchida, Hideo, Kamino, Keiji, Nishimura, Yukihiro, Ohishi, Hajime, Takayasu, Yukio, Miura, Kohi, Nakao, N, Uchida, H, Kamino, K, Nishimura, Y, Ohishi, H, Takayasu, Y, Miura, K
Zdroj: CardioVascular & Interventional Radiology; Mar1994, Vol. 17 Issue 2, p76-80, 5p
Abstrakt: Purpose: Multivariate analysis was used to study the effectiveness and optimum dose level of Lipiodol (LP) in transcatheter arterial embolization (TAE) of hepatocellular carcinoma (HCC).Methods: A total of 219 cases of nodular type HCC, with a tumor diameter less than 7 cm, were studied. TAE was performed using both Gelfoam sponge (GS) and LP in 158 cases; in the remaining 61 cases only GS was used.Results: Statistical stepwise variable selection revealed that only LP had a negative T-value, suggesting that LP is a useful factor for prognosis. The most favorable effect on patient prognosis was obtained with an LP dose level (expressed in mm) of 1-1.5 times the absolute value of the tumor diameter (expressed in cm).Conclusion: A significant difference (p < 0.01, log-rank test) in survival was found between the GS with LP group and the GS only group, using Cox's proportional hazard model. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index