Coxiella burnetii infection among subjects infected with HIV type 1 in the Central African Republic.

Autor: Bélec, L., Grésenguet, G., Ekala, M., Jacob, A., Vohito, M., Cotigny, S., Payan, C.
Zdroj: European Journal of Clinical Microbiology & Infectious Diseases; Oct1993, Vol. 12 Issue 10, p775-778, 4p
Abstrakt: Sixty-six sera from HIV-1-seropositive adult African subjects and 49 sera from HIV-seronegative age and sex matched healthy African controls living in Bangui, Central African Republic, were screened for Coxiella burnetii antibody by an indirect immunofluorescent antibody test. 16.7 % of HIV-infected patients and 16.3 % of the HIV-negative controls had positive IgG titres, with no significant difference between the two groups. Two of the seven HIV-infected patients seropositive for Coxiella burnetii for whom clinical data was available had a medical history compatible with symptomatic Q fever. These findings indicate that there is a high degree of exposure to Coxiella burnetii infection in Bangui. In individuals co-infected with HIV and Coxiella burnetii, cellular immunosuppression could favour symptomatic Q fever. Physicians should be aware of the possibility of symptomatic Coxiella burnetii infection among HIV-infected people, particularly in endemic regions for both infections such as in sub-saharan Africa. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index