Local cerebral blood flow measured by stable xenon CT during fentanyl-diazepam anesthesia.

Autor: Kawaguchi, Masahiko, Kuro, Masakazu, Ohsumi, Hisatoshi, Nakajima, Toshito, Kuriyama, Yoshihiro, Karasawa, Jun
Zdroj: Journal of Anesthesia; Mar1994, Vol. 8 Issue 1, p60-63, 4p
Abstrakt: We assessed the local cerebral blood flow (LCBF) in 40 patients under fentanyl-diazepam anesthesia. The measurement of LCBF was made using 50%-70% stable xenon with 20 min of inhalation interval and a shuttle method for computed tomography imaging. All patients were anesthetized with 5.95±1.76 μg·kg fentanyl and 0.22±0.07 mg·kg diazepam under mechanical ventilation during CBF measurement. The values and distribution of LCBF on non-affected hemisphere appeared to be unaltered by fentanyldiazepam anesthesia. We also assessed the cerebral carbon dioxide reactivity in 6 patients. The cerebral carbon dioxide reactivity, expressed as percentage change in LCBF per unit change in arterial carbon dioxide partial pressure, was 5.39±1.07, and there were no significant differences of reactivity among regions studied. In conclusion, we showed reference values of LCBF and carbon dioxide reactivity, measured by stable xenon-enhanced computed tomography, in patients under fentanyl-diazepam anesthesia. Carbon dioxide reactivity was preserved in all regions including gray matter, white matter, and basal ganglia. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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