| Autor: |
Paramsothy, M., Zainuddin, J., Low, K. |
| Zdroj: |
Lasers in Medical Science; Dec1989, Vol. 4 Issue 4, p205-210, 6p |
| Abstrakt: |
The in vivo uptake of Tc-99m-labelled HpD in a murine tumour has been investigated using nuclear imaging techniques. Eighty-four per cent of the palpable tumours were visualized with good contrast resolution. The peak tumour-to-surrounding-normal-tissue ratio of 5:1 was at 4 h post-injection indicating the optimum time of imaging. The high level of HpD in the blood-pool component of the tumour could indicate that photodynamic therapy administered within 2 h after intravenous injection ('early PDT') could lead to damage of tumour vasculature and tumour necrosis. The therapeutic response achieved by this early method needs to be investigated. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink