Autor: |
Bianchetti, Mario, Roduit, Claudio, Oetliker, Oskar |
Zdroj: |
Pediatric Nephrology; Mar1991, Vol. 5 Issue 2, p238-239, 2p |
Abstrakt: |
Of 19 children treated with high-dose intravenous acyclovir, 7, all of whom had encephalitis, also had a restricted fluid intake. Of these, 3 experienced nonoliguric renal insufficiency (plasma creatinine up to 176, 250 and 351 μmol/l, respectively) which resolved within 1 week of discontinuing acyclovir. Renal function was stable in the remaining 4 patients in this group and in the 12 children treated with acyclovir but without fluid restriction. We suggest the decreased renal function resulted from intratubular acyclovir crystalluria. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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