Pyrophosphate inhibition of calcium oxalate dihydrate crystallization in simulated urine: Continuous flow studies.

Autor:	Drach, G., Robertson, W., Scurr, D., Randolph, A.
Zdroj:	World Journal of Urology; Aug1983, Vol. 1 Issue 3, p146-149, 4p
Abstrakt:	Calcium oxalate crystal growth rate and nucleation rate, as well as total crystal mass, were linearly decreased by addition of sodium pyrophosphate to simulated urine over the range 0.1-0.6 mmol·1. These observations suggest that complexation with free ionic calcium plays a part in the inhibition produced. Pyrophosphate may therefore have a dual mechanism of inhibition: surface active at lower concentrations and complexation at higher concentrations. This latter mechanism may be active after oral orthophosphate therapy. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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