| Autor: |
Arisaka, Madoka, Arisaka, Osamu, Hosaka, Atsuto, Tokita, Akifumi, Shimura, Naoto, Yabuta, Keijiro, Kawaguchi, Yoshindo |
| Zdroj: |
Journal of Bone & Mineral Metabolism; Aug1989, Vol. 7 Issue 2, p18-22, 5p |
| Abstrakt: |
We describe a 16-year-old boy with idiopathic hypogonadotropic hypogonadism associated with osteoporosis. Osteoporotic lesions of the hands, skull and spine were shown by routine radiography. Single-photon absorptiometry at the distal radius confirmed a significant reduction of bone mineral density. The parathyroid hormone-vitamin D axis and calcitonin secretion showed no derangement. Reduced bone mineral density in association with relatively elevated levels of serum osteocalcin and alkaline phosphatase suggested an increased bone turnover (so-called high-turnover osteoporosis). Tetosterone therapy for 3 months significantly increased the radial bone mineral density. This case illustrates that testosterone deficiency during puberty seems to alter the bone mineral status, impairing bone mineralization and bone remodeling. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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