| Autor: |
Fujimori, Akira, Tsutsumi, Masaharu, Yamada, Hajime, Fukase, Masaaki, Noda, Toshiharu, Fujii, Nobutaka, Fujita, Takuo |
| Zdroj: |
Journal of Bone & Mineral Metabolism; Dec1988, Vol. 6 Issue 3, p26-29, 4p |
| Abstrakt: |
The effects of amino-terminal fragments of human parathyroid hormone (hPTH 1-34) and the human parathyroid hormone-related protein (hPTHrP 1-34, Tyr-hPTHrP 1-40) on cell growth and alkaline phosphatase activity were studied in an osteoblastic cell line, MC3T3-E1. The three peptides were equipotent in suppressing DNA synthesis and alkaline phosphatase activity. These results suggest that the three peptides have similar post-receptor effects in osteoblasts probably through the same receptor sites. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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