Autor: |
Gaskill, Sarah, Marlin, Arthur, Saldivar, Victor |
Zdroj: |
Child's Nervous System; Aug1988, Vol. 4 Issue 4, p237-240, 4p |
Abstrakt: |
Since its first description by Kepes in 1979, pleomorphic xanthoastrocytoma (PXA) has been considered a tumor with a benign course. Two cases are presented here that support the concept that PXA may be more accurately considered part of a spectrum of astrocytomas that occasionally may act aggressively. These cases represent astrocytomas with PXA components and are characterized by meningeal proximity, a high number of mitoses, and subsequently aggressive clinical behavior. The importance of recognizing the potential of a 'benign' PXA to transform into a malignant entity has obvious implications for the therapeutic management of these tumors. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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