Glioblastoma multiforme masquerading as a pleomorphic xanthoastrocytoma.

Autor: Gaskill, Sarah, Marlin, Arthur, Saldivar, Victor
Zdroj: Child's Nervous System; Aug1988, Vol. 4 Issue 4, p237-240, 4p
Abstrakt: Since its first description by Kepes in 1979, pleomorphic xanthoastrocytoma (PXA) has been considered a tumor with a benign course. Two cases are presented here that support the concept that PXA may be more accurately considered part of a spectrum of astrocytomas that occasionally may act aggressively. These cases represent astrocytomas with PXA components and are characterized by meningeal proximity, a high number of mitoses, and subsequently aggressive clinical behavior. The importance of recognizing the potential of a 'benign' PXA to transform into a malignant entity has obvious implications for the therapeutic management of these tumors. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index