| Autor: |
Eggers, Arnold, Tarmin, Lila, Ginsburg, Sara |
| Zdroj: |
Cancer Immunology, Immunotherapy; Feb1982, Vol. 12 Issue 2, p167-172, 6p |
| Abstrakt: |
Mice were immunized in vitro and in vivo against the tumor-associated antigens of a methylcholanthrene-induced tumor, with immunogen cells coupled to the p-nitrophenyl ester of N-acetylmuramyl- l-alanyl- d-isoglutamine (adjuvant peptide). Immune activity was measured either with a short-term chromium release assay or by following the regression of small tumors. Interposing a glycylglycylcystamide spacer between the adjuvant peptide and the tumor cell surface further increased tumor immunogenicity. Beige mice developed good anti-tumor immunity, whereas nude mice developed none. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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