| Autor: |
Sørensen, Jens, Bach, Flemming, Dombernowsky, Per, Hansen, Heine, Sørensen, J B, Bach, F, Dombernowsky, P, Hansen, H H |
| Předmět: |
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| Zdroj: |
Cancer Chemotherapy & Pharmacology; Nov1991, Vol. 27 Issue 6, p487-489, 3p |
| Abstrakt: |
A total of 26 evaluable patients with previously untreated, non-resectable adenocarcinoma of the lung were given 80 mg/m2 i.v. teniposide daily for 5 days every 3 weeks. Three partial responses (11%) were obtained that lasted for 12, 11 and 32 weeks, respectively. Leucopenia was the dose-limiting side effect, with WBC counts of less than 2 x 10(9)/l being observed in 42% of patients, resulting in one septic death. At the dose and schedule used in the present study, teniposide showed only limited activity in adenocarcinoma of the lung. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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