| Autor: |
Kushibe, Keiji, Iioka, Sogo, Nezu, Kunimoto, Tojo, Takashi, Sawabata, Noriyoshi, Kitamura, Soichiro |
| Zdroj: |
Surgery Today; Apr1995, Vol. 25 Issue 4, p334-337, 4p |
| Abstrakt: |
In this study, the prognostic value of determining the nuclear DNA content of thymomas by flow cytometry was evaluated. Of a total 31 resected thymomas, 10 (32%) showed DNA aneuploidy, the presence of which was significantly correlated with an advanced clinical stage of disease. The patients with an aneuploid tumor had a poorer prognosis than those with a diploid tumor, demonstrating a survival rate of 50% at 7 postoperative years, which was considerably less favorable than that of the patients with a diploid tumor, being 100% in the same period ( p<0.05). Moreover, patients with a high DNA index (DI), i.e., a DI≧1.5, tended to have a poorer prognosis than those with a low DI. These findings indicated that the DNA content can be an important prognostic index in patients with thymomas. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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