Penicillium aurantiogriseum Dierckx produces chaetoglobosin A toxic to embryonic chickens.

Autor: Veselý, Drahomír, Veselá, Doubravka, Jelínek, Richard
Zdroj: Mycopathologia; Oct1995, Vol. 132 Issue 1, p31-33, 3p
Abstrakt: Several strains of the genus Penicillium isolated from swabs from uranium miners working environment were screened for production of known mycotoxins; and embryotoxicity of chloroform extracts from the isolates was investigated in chick embryos. Penicillium aurantiogriseum was found to produce chaetoglobosin A. ED of this mycotoxin for 2-, 3- and 4-day-old chick embryos was found 0.040 (0.031-0.052), 0.074 (0.051-0.107), and 0.180 (0.113-0.229) µg/embryo, respectively. The effect was purely embryolethal with no signs of teratogenicity recorded. This is the first report on the isolation of chaetoglobosin A from the genus Penicillium. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index