Evidence for enzymatic reduction of 1-nitropyrene by rat liver fractions.
| Autor: | Nachtman, J., Wei, E. |
|---|---|
| Zdroj: | Experientia; Jul1982, Vol. 38 Issue 7, p837-838, 2p |
| Abstrakt: | 1-Nitropyrene, a mutagenic compound found in diesel exhaust and photocopy toners, is reduced anaerobically by rat liver fractions to 1-aminopyrene. This reaction is stimulated in the microsomal fraction by NADPH and in the cytosol by FMN. Addition of both cofactors produced more reduction in S-9, microsomes, or cytosol than either cofactor alone. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
| Externí odkaz: |
|