| Abstrakt: |
Lactic acidosis is a rare but serious complication of the use of biguanides in anti-diabetic therapy. This report details two cases of diabetic lactic acidosis secondary to Metformin, successfully treated by peritoneal dialysis, using sodium acetate as the dialyzing substance. The author emphasizes the use of extra-renal purification, and more specifically peritoneal dialysis, as symptomatic therapy of lactic acidosis in the diabetic patient. Acetate, rather than lactate, as the dialyzing substance, is most justified from a biochemical point of view. [ABSTRACT FROM AUTHOR] |
Full text from SpringerLink