| Abstrakt: |
The effects of PCBs (polychlorinated biphenyls) or a combination of DDT (1,1,1-trichloro-2,2- bis (p-chlorophenyl) ethane), DDD (1,1-dichloro-2,2- bis (p-chlorophenyl) ethane) and DDE (1,1-dichloro-2,2- bis (p-chlorophenyl ethylene) on organ weights, liver storage of vitamin A and carotene, selected blood chemistry parameters, and serum protein fractions were determined in penned white pelicans ( Pelecanus erythrorhynchos) receiving a daily dosage of these compounds. Birds received 100 mg of PCBs or a combination of DDT (20 mg), DDD (15 mg), and DDE (15 mg) injected into the first fish fed each day for ten weeks. A greater percentage of PCB treatment was retained in brain, liver, carcass and feathers than the percentage of DDT + DDD + DDE treatment. Liver weight as percent of body weight decreased (p<0.01) in DDT + DDD + DDE-treated birds and increased (p<0.01) as a total weight in PCB-treated birds. Spleen weight as percent of body weight was greater (p<0.05) in PCB-treated birds. Neither treatment had a significant effect on the weight of the brain, heart, or kidney. Liver vitamin A levels were greater (p<0.01) on a μg/g of liver basis in the DDT-treated birds than in controls. Significant lowering of serum potassium and protein values was noted in both the PCB- and the combination of DDT, DDD, DDE-treated birds, while serum calcium values were lowered (p<0.01) only in PCB-treated birds. Values of serum inorganic phosphorus, uric acid and magnesium were not significantly changed by either treatment. Globulin fractions were unaltered by either treatment, but albumin fractions were lowered (p<0.01) in the PCB-treated pelicans. [ABSTRACT FROM AUTHOR] |
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