Diaphyseal telangiectatic osteosarcoma as a second tumor after bilateral retinoblastomas.

Autor: Brown, Maura J., Logan, P. Mark, O'Connell, John X., Janzen, D. L., Connell, Douglas G., Brown, M J, Logan, P M, O'Connell, J X, Connell, D G
Zdroj: Skeletal Radiology; Oct1996, Vol. 25 Issue 7, p685-688, 4p
Abstrakt: In this report, we describe the clinical, imaging, and pathologic findings in a case of diaphyseal telangiectatic osteosarcoma arising 23 years after successful treatment of bilateral retinoblastomas. To our knowledge, telangiectatic osteosarcoma occurring as a second tumor in this setting, outside the radiation treatment field, has not been previously reported. The association of the RB-1 gene defect with retinoblastomas and other tumors is discussed. Also, the computed tomography and magnetic resonance imaging findings in telangiectatic osteosarcoma are described and discussed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index