| Autor: |
Doxiadis, Gabriele, Schoen, Wolfram, Doxiadis, Ilias, Joachim Deeg, H., O'Neill, Goeffrey, Grosse-Wilde, Hans |
| Zdroj: |
Immunogenetics; 1987, Vol. 25 Issue 3, p167-170, 4p |
| Abstrakt: |
As a collaborative work of three laboratories the polymorphism of the canine fourth complement component (C4) was studied in a total of 131 unrelated dogs from different breeds and mongrels. Using high voltage electrophoresis followed by an immunoblotting technique, we detected eight distinct variants. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) of canine C4 showed an additional heterogeneity of the α and γ chains which resulted in a total of 11 variants in the population studied. So that more precise information concerning the respective C4 allotypes will be available, a nomenclature is proposed designating not only the migration pattern of the C4 variants in agarose gels but also the heterogeneity of the C4 chains observed in SDS-PAGE. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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