| Autor: |
Flaherty, Lorraine, Karl, Margaret, Reinisch, Carol |
| Zdroj: |
Immunogenetics; 1982, Vol. 16 Issue 4, p329-337, 9p |
| Abstrakt: |
BALB/cBy (Qa-2) mice injected with the syngeneic tumor, ORA I-a (Qa-2), produced antibodies to Qa-2 and a newly discovered antigen, Qa-6. Specific antisera against Qa-6, in the presence of complement, lyses approximately 40% of lymph-node lymphocytes and splenocytes. Strain distribution analyses indicate that Qa-6 is specified by a gene within the TL subregion of the major histocompatibility complex. Thus, Qa-6 is the third member of the Qa/TL subset of cell surface antigens which is anomalously expressed on certain tumor cells. This finding suggests that the Qa and TL molecules may have a unique, functional role on the cell surface. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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