| Autor: |
Flaherty, Lorraine, Rinchik, Eugene, DiBiase, Kathleen |
| Zdroj: |
Immunogenetics; 1981, Vol. 13 Issue 4, p339-346, 8p |
| Abstrakt: |
Mouse strain and tissue distribution analyses indicate that the new antiserum A anti-A- Tla recognizes the cell-surface product governed by the previously serologically undetectable Qa-I allele. This cell-surface product has therefore been called Qa-1.2. Three levels of anti-Qa-1.2 cytotoxicity in the presence of complement have been observed: high, intermediate, and zero lysis. In general, high levels of lysis correlate with the presence of the Qa-1 b allele, while zero levels of lysis correlate with the presence of the Qa-1allele. The A.CA strain reacts with both anti-Qa-1.1 and anti-Qa-1.2 and may possess a third allele, Qa-1. Several strains including B6- H-2 react in an intermediate fashion. Recombinant strain analyses indicate that this intermediate reaction may be due to modifying genes within the H-2D region. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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