| Autor: |
Pink, J., Droege, W., Hála, K., Miggiano, V., Ziegler, A. |
| Zdroj: |
Immunogenetics; 1977, Vol. 5 Issue 1, p203-216, 14p |
| Abstrakt: |
The major histocompatibility complexes ( B complexes) of chickens of various origins have been studied by serological and biochemical methods. Two B complexes are of particular interest: B, a recombinant haplotype derived from the B complexes of the inbred CB and CC strains, and B, the B haplotype of the G-B1 strain. The B haplotype differs detectably from the B haplotype only at a locus controlling the synthesis of an antigen, B-G, which (in peripheral blood) is present only on red cells. Anti-B-G sera precipitate, fromI-labeled red cell lysates, two chains of apparent molecular weights 42,000 and 31,000 (measured under reducing conditions); the smaller is perhaps derived by proteolysis from the larger. The B haplotype differs detectably from the B haplotype only at a locus controlling the synthesis of an antigen whose tissue distribution and biochemical and biological properties are identical to those of B-G. The chicken major histocompatibility complex therefore contains at least three loci-those controlling synthesis of the B-G, and of the previously defined B and B-L antigens. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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