| Autor: |
Sugisaki, Tetsuro, Beamer, Wesley, Noguchi, Tetsuya |
| Zdroj: |
Neurochemical Research; Oct1992, Vol. 17 Issue 10, p1037-1040, 4p |
| Abstrakt: |
2′,3′-Cyclic nucleotide 3′-phosphohydrolase activity in the cerebrum of the congenital goiter mouse ( cog/cog) is reduced in comparison with the normal heterozygote ( cog/+). The weight of the cog/cog cerebrum and cerebellum were significantly less than those of the normal controls, 89.0% less for the cerebrum, and 81.1% less for the cerebellum. However, no differences were observed with regard to DNA and RNA content and the RNA/DNA ratio. The results of this study indicate that hypomyelination in the congenital goiter mouse is restricted to the cerebrum, and is not related to arrested glial proliferation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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