Purification of guanine deaminase inhibitor from human brain.

Autor: Kumar, Sudhir, Rathi, Manohar
Zdroj: Neurochemical Research; May1980, Vol. 5 Issue 5, p547-550, 4p
Abstrakt: A procedure for the purification of guanine deaminase inhibitor from human brain mitochondria is described. The inhibitor was enriched about 150-fold with recoveries of over 65%. It is nondialyzable, insoluble in water, and stable for over 30 days at−16°C. However, the protein is completely inactivated at 50°C in 5 min. The purified protein also inhibits the activities of a number of other enzymes. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index