Impact of Introducing the Pneumococcal and Rotavirus Vaccines Into the Routine Immunization Program in Niger.

Autor: Lee, Bruce Y., Assi, Tina-Marie, Rajgopal, Jayant, Norman, Bryan A., Chen, Sheng-I, Brown, Shawn T., Slayton, Rachel B., Kone, Souleymane, Kenea, Hailu, Welling, Joel S., Connor, Diana L., Wateska, Angela R., Jana, Anirban, Wiringa, Ann E., Panhuis, Willem G. Van, Burke, Donald S.
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Zdroj: American Journal of Public Health; Feb2012, Vol. 102 Issue 2, p269-276, 8p
Abstrakt: Objectives. We investigated whether introducing the rotavirus and pneumococcal vaccines, which are greatly needed in West Africa, would overwhelm existing supply chains (i.e., the series of steps required to get a vaccine from the manufacturers to the target population) in Niger. Methods. As part of the Bill and Melinda Gates Foundation-funded Vaccine Modeling Initiative, we developed a computational model to determine the impact of introducing these new vaccines to Niger's Expanded Program on Immunization vaccine supply chain. Results. Introducing either the rotavirus vaccine or the 7-valent pneumococcal conjugate vaccine could overwhelm available storage and transport refrigerator space, creating bottlenecks that would prevent the flow of vaccines down to the clinics. As a result, the availability of all World Health Organization Expanded Program on Immunization vaccines to patients might decrease from an average of 69% to 28.2% (range=10%-51%). Addition of refrigerator and transport capacity could alleviate this bottleneck. Conclusions. Our results suggest that the effects on the vaccine supply chain should be considered when introducing a new vaccine and that computational models can help assess evolving needs and prevent problems with vaccine delivery. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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