| Autor: |
Jacob, Chaim O., Eisenstein, Miriam, Dinauer, Mary C., Ming, Wenyu, Liu, Qiang, John, Sutha, Quismorio Jr., Francesco P., Reiff, Andreas, Myones, Barry L., Kaufman, Kenneth M., McCurdy, Deborah, Harley, John B., Silverman, Earl, Kimberly, Robert P., Vyse, Timothy J., Gaffney, Patrick M., Kathy L. Moser, Klein-Gitelmant, Marisa, Wagner-Weiner, Linda, Langefeld, Carl D. |
| Předmět: |
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| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; 1/10/2012, Vol. 109 Issue 2, p359-360, 2p |
| Abstrakt: |
The article focuses on new developed alternative bioinformatics-driven method to decrease the test needed in analyzing genetic disease. It says an applied methodology is used to discover genes associated with systematic lupus erythematosus (SLE). Results show that a single identified mutation in neutrophil cytosolic factor (NCF2) contributes to the reduction of reactive oxygen species (ROS) production and that NCF2 plays a significant function in predisposition to SLE. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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