| Autor: |
Regatieri, Alessandra, Abdelwahed, Yehia, Perez, Maria T., Bush, Larry M. |
| Předmět: |
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| Zdroj: |
Laboratory Medicine; Jan2011, Vol. 42 Issue 1, p11-16, 6p, 2 Color Photographs |
| Abstrakt: |
The identification of latent tuberculosis infection (LTBI) in any individual or population has proven to carry significant importance not only for that person's health, but also for the control and eventual elimination of tuberculosis (TB) in the United States. Traditionally, the tuberculin skin test (TST) has served as the standard of care for the identification of prior exposure to Mycobacterium tuberculosis (MTB). However, the specificity of a positive test is less than optimal. It is either due to previous vaccination intended to prevent TB or infection with nontuberculous mycobacterium (NTM). Newer tests classified as interferon-gamma release assays (IGRA) possess potential advantages over the TST when used for identifying those with MTB infection. We recently diagnosed a case of pleuropulmonary infection involving an unusual NTM, Mycobacterium interjectum (M. interjectum), in an immunocompromised man diagnosed 1 year after he had been treated for LTBI based on a reactive TST. A propos this experience, we discuss the beneficial role of IGRAs and review the literature on infection with M. interjectum. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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