Effect of pre-operative anxiolysis on postoperative pain response in patients undergoing total abdominal hysterectomy.

Autor: Caumo, W., Hidalgo, M. P. L., Schmidt, A. P., Iwamoto, C. W., Adamatti, L. C., Bergmann, J., Ferreira, M. B. C.
Předmět:
Zdroj: Anaesthesia; Aug2002, Vol. 57 Issue 8, p740-746, 7p
Abstrakt: Summary In a double blind, placebo-controlled trial, we have assessed the effects of pre-operative anxiolysis on postoperative pain scores in 112 ASA I-II women, aged 18–65 years, scheduled to undergo total abdominal hysterectomy. Subjects were randomly allocated to receive either oral diazepam 10 mg (n =56) or placebo ( n =56) pre-operatively. Postoperative anxiety, pain scores, analgesic consumption, and sedation were evaluated at several time points during the first 24 h following surgery. Postoperative pain scores were found to be significantly higher in the diazepam group. Trait and state anxiety showed a significant effect on pain scores, independent of the treatment group. No difference was found between the groups in morphine consumption, but there was a significant reduction in morphine consumption with time. [ABSTRACT FROM AUTHOR]
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