Nosocomial transmission of delta hepatitis.

Autor: Lettau, Ludwig A., Alfred, Howard J., Glew, Richard H., Fields, Howard A., Alter, Miriam J., Meyer, Richard, Hadler, Stephen C., Maynard, James E., Lettau, L A, Alfred, H J, Glew, R H, Fields, H A, Alter, M J, Meyer, R, Hadler, S C, Maynard, J E
Předmět:
Zdroj: Annals of Internal Medicine; May86, Vol. 104 Issue 5, p631-635, 5p, 1 Chart, 1 Graph
Abstrakt: A previously asymptomatic carrier of hepatitis B virus receiving chronic hemodialysis developed acute delta hepatitis. The patient regularly received dialysis treatments on the same machine as a parenteral drug abuser with hepatitis B surface antigen (HBsAg)-positive chronic hepatitis whose serum was strongly positive for delta antibody. The drug abuser had a major bleeding episode that caused extensive environmental contamination 3 months before onset of illness in the index patient. No other patients receiving dialysis or staff members had evidence of delta infection. A surgeon previously infected with hepatitis B from the same parenteral drug abuser also had delta antibody. Testing for delta virus is indicated for both HBsAg-positive parenteral drug abusers and patients with hemophilia receiving chronic hemodialysis. All patients who are HBsAg- and delta-positive should receive dialysis separately from patients who are HBsAg-positive and delta-negative. Susceptible patients on dialysis and staff should receive hepatitis B vaccine to protect against both hepatitis B and delta virus infection. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index