| Autor: |
Ahmed, Sulaiman, Sumera, Afshan, Mustanssar, Tazeen, Mirza, Talat, Agha, Akbar, Khanani, Rafiq |
| Předmět: |
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| Zdroj: |
Medical Channel; Oct2010, Vol. 16 Issue 4, p637-639, 3p, 3 Charts |
| Abstrakt: |
OBJECTIVE: To describe the pattern of presentation of tuberculous lymphadenitis, to correlate the sensitivity of Fine Needle Aspiration Cytology (FNAC) and Ziehl Neelsen (ZN) stain in the diagnosis of Tuberculosis (TB) lymphadenitis and to assess the diagnostic yield of FNAC in cervical lymphadenopathy. STUDY DESIGN: Prospective cross sectional study. METHODS: Total one hundred and sixty four patients of clinically suspected TB lymphadenitis, referred to Dow Diagnostic Reference & Research Laboratory (DDRRL) for diagnostic services for lymphadenopathy from Jan 2008 to Oct 2009 were included. Cytological evaluation for identification of Acid Fast Bacilli (AFB) was done on separate slides with Hematoxylin & Eosin (H & E) & ZN (hot method) stain. RESULTS: Mean age was 24.49; Female were 69%; Male were 31%. Out of 164, tubercular were 117(71.3%) & 17(10.4%) were of reactive nature. The remaining 9(5.5%) cases were of malignant lymphadenopathy, consisting 1(0.6%) case of primary malignancy i.e. lymphoma and 8(4.9%) of metastasis to lymph nodes. Overall 11 cases (6.7%) were found positive for AFB on ZN stain. CONCLUSION: Cytomorphologic diagnostic features of FNAC on H&E stain have significant diagnostic yield. FNAC is an optimally selected, efficient, easy to perform and economical test for initial diagnostic workup in patients with TB Lymphadenitis in Pakistan. Supplementation of ZN stain does not add to the overall Positive Predictive Value of FNAC. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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