Phosphoribosylpyrophosphate in man: biochemical and clinical significance.
| Autor: | Fox, Irving H., Kelley, Williman N., Fox, I H, Kelley, W N |
|---|---|
| Předmět: |
PYROPHOSPHATES
PURINE synthesis METABOLISM PURINE metabolism ADRENOCORTICOTROPIC hormone ANIMALS GLYCOGEN GOUT INBORN errors of metabolism METHYLENE blue MONOSACCHARIDES OXIDOREDUCTASES PHOSPHORIC acid PURINES SUGAR phosphates THIAZOLES THYROTROPIN TRANSFERASES URIC acid ALLOPURINOL CHEMICAL inhibitors PHARMACODYNAMICS |
| Zdroj: | Annals of Internal Medicine; Mar71, Vol. 74 Issue 3, p424-433, 10p |
| Abstrakt: | Examines the critical role of intracellular concentration of phosphoribosylpyrophosphate (PRPP) in the regulation of purine metabolism in man. Biochemistry of PRPP; Catabolism of PRPP by a series of phosphoribosyltransferase enzymes; Alteration of intracellular PRPP in human disease. |
| Databáze: | Complementary Index |
| Externí odkaz: |
|