Activation of cardiac ryanodine receptors by the calcium channel agonist FPL-64176.

Autor: Wasserstrom, J. Andrew, Wasserstrom, Leslie A., Lokuta, Andrew J., Kelly, James E., Reddy, Sireen T., Frank, Andrew J.
Předmět:
Zdroj: American Journal of Physiology: Heart & Circulatory Physiology; Jul2002, Vol. 283 Issue 1, pH331, 8p, 6 Graphs
Abstrakt: Presents a study that investigated the possibility that the calcium (Ca) ²+; channel agonist fpl-64176 (FPL) might also activate the cardiac sacroplasmic reticulum (SR) Ca²+; release channel ryanodine receptor. Effects of FPL on purified human RyR2; Effects of FPL on channel activity in dog SR vesicles; Effects of FPL on open and closed characteristics of dog SR channels.
Databáze: Complementary Index