Domino as a bridge to definitive liver transplantation in a neonate.

Autor: Casas-Melley, Adela T, Thomas, Philip G, Krueger, Leslie J, Falkenstein, Kathleen P, Flynn, Louise M, Conley, Susan B, Dunn, Stephen P
Předmět:
Zdroj: Pediatric Transplantation; Jun2002, Vol. 6 Issue 3, p249-254, 6p
Abstrakt: Abstract: An interim liver transplant was used to extend survival in a neonate. This was accomplished by the initial transplant of a left-lateral segment of a metabolically abnormal liver obtained from a 7-yr-old patient with primary oxalosis. This bridging strategy was required because our neonatal patient was dying of fulminant hepatic failure caused by hepatic vein thrombosis and a small liver or liver segment could not be found. Although problems with hyperoxaluria were encountered in the neonate post-transplant, the interim liver transplant enabled the baby to survive and grow until the age of 4 months. At that time, a definitive transplant was performed using the left-lateral segment of his mother's liver. This case represents the first reported use of a pediatric domino transplant where a metabolically abnormal liver was used to allow sufficient growth to permit a definitive liver transplantation. [ABSTRACT FROM AUTHOR]
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