| Autor: |
Tashima, K. T., Flanigan, T. P., Kurpewski, J., Melanson, S. M., Skolnik, P. R. |
| Předmět: |
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| Zdroj: |
Clinical Infectious Diseases; 7/1/2002, Vol. 35 Issue 1, p82-83, 2p |
| Abstrakt: |
Discordant resistance mutations were seen in human immunodeficiency virus type 1 (HIV-1) isolated from specimens of blood and cerebrospinal fluid (CSF) obtained from 3 of 6 patients. To our knowledge, this is the first report of HIV-1 isolated from CSF harboring the K103N mutation, which confers resistance to the nonnucleoside reverse-transcriptase inhibitors, and this finding may indicate that virus in the CSF replicates independently from virus in the blood compartment. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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