| Autor: |
Traverse, Jay H., Henry, Timothy D., Ellis, Stephen G., Pepine, Carl J., Willerson, James T., Zhao, David X. M., Forder, John R., Byrne, Barry J., Hatzopoulos, Antonis K., Penn, Marc S., Perin, Emerson C., Baran, Kenneth W., Chambers, Jeffrey, Lambert, Charles, Raveendran, Ganesh, Simon, Daniel I., Vaughan, Douglas E., Simpson, Lara M., Gee, Adrian P., Taylor, Doris A. |
| Předmět: |
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| Zdroj: |
JAMA: Journal of the American Medical Association; 11/16/2011, Vol. 306 Issue 19, p2110-2119, 10p, 2 Diagrams, 4 Charts |
| Abstrakt: |
The article discusses a study on the impact of intracoronary delivery of autologous bone marrow mononuclear cells (BMCs) on left ventricular (LV) function when administered two to three weeks after myocardial infarction (MI). The study was a randomized controlled trial known as the LateTIME trial in the U.S. involving 87 patients who had LV dysfunction following primary percutaneous coronary intervention (PCI). Cardiac magnetic resonance imaging was used to measure changes in global and regional LV function. The researchers found that intracoronary infusion of autologous BMCs had no significant impact on global or regional LV function at six months compared with intracoronary placebo infusion. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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