| Autor: |
Martin, E., Ruf, E., Landgraf, R., Hauner, H., Weinauer, F., Martin, S. |
| Předmět: |
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| Zdroj: |
Hormone & Metabolic Research; Oct2011, Vol. 43 Issue 11, p782-787, 6p |
| Abstrakt: |
Despite the efforts to control the epidemic of diabetes the total number of people living with diabetes is still steadily rising. In order to detect people at risk, cost-effective, convenient, and sensitive screening tools to assess the diabetes risk and to detect undiagnosed type 2 diabetes need to be developed and implemented in the primary care setting. To evaluate the combination of the well established FINDRISK questionnaire and HbA1c testing as a potential screening strategy the data obtained from 671 blood donors were analyzed for a potential correlation with the results of an oral glucose tolerance test. Based on the oral glucose tolerance test, 65 blood donors (9.7 %) were newly diagnosed with diabetes, 336 (50.1 %) with prediabetes, and 270 (40.2 %) had a normal test result. Of the 401 blood donors diagnosed with prediabetes or diabetes 322 (80.3 %) had a HbA1c between 5.7 % and 6.4 % and 27 (6.7 %) with a HbA1c of 6.5 % or greater. The majority of the blood donors newly diagnosed with diabetes or prediabetes (n = 327) had a FINDRISK result of 12 points or higher. ROC analyses confirmed that the optimal cut off levels were for FINDRISK ≥ 12 points and for HbA1c ≥ 5.9 %. Thus, a 3-step screening strategy applying the FINDRISK questionnaire followed by HbA1c testing and performing an oral glucose tolerance test on selected individuals could be a cost-saving approach for screening large populations and identifying people at risk for diabetes or undiagnosed diabetes. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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