| Autor: |
Badner, N. H., Goure, C., Bennett, K. E., Nicolaou, G. |
| Předmět: |
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| Zdroj: |
HSR Proceedings in Intensive Care & Cardiovascular Anesthesia; Sep2011, Vol. 3 Issue 3, p189-194, 6p |
| Abstrakt: |
Introduction: In multiple study populations large tidal volumes (8 - 12 ml/kg) have deleterious effects on lung function in multiple study populations. The accepted approach to hypoxemia during one-lung ventilation is the application of continuous positive airway pressure to the non-ventilated lung first, followed by application of positive end-expiratory pressure to the ventilated lung. To our knowledge the effectiveness of positive end-expiratory pressure or continuous positive airway pressure on maintaining Pao2 with one-lung ventilation was not studied with smaller tidal volume (6ml/kg) ventilation. our objective was to compare continuous positive airway pressure of 5 cm H2O or positive end-expiratory pressure of 5 cm H2O during small tidal volume one-lung ventilation. Methods: Thirty patients undergoing elective, open thoracotomy with one-lung ventilation were randomized to continuous positive airway pressure or positive end-expiratory pressure and then crossed over to the other modality. results: There was a statistically significant higher PaO2 (141±81.6 vs 112±48.7, p = 0.047) with continuous positive airway pressure than positive end-expiratory pressure while on one-lung ventilation. Two patients desaturated requiring 100% O2 with both positive end-expiratory pressure and continuous positive airway pressure. on two occasions the surgeon requested the continuous positive airway pressure be discontinued due to lung inflation. Conclusion: The use of continuous positive airway pressure of 5 cm H2O to the non-ventilated lung while using small tidal volumes for one-lung ventilation improved PaO2 when compared with positive end-expiratory pressure of 5 cm H2O to the ventilated lung. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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