| Autor: |
Talaei, Afsaneh, Jabari, Saber, Bigdeli, Mohamad Hasan, Farahani, Heidar, Siavash, Mansour |
| Předmět: |
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| Zdroj: |
Indian Journal of Endocrinology & Metabolism; Oct2011, Vol. 15 Issue 4, p316-319, 4p |
| Abstrakt: |
Introduction: Diabetes mellitus and its chronic complications may be associated with alterations in the plasma, tissue, and urinary levels of some trace elements like copper. Materials and Methods: This cross-sectional study evaluates the 24 hour urinary copper levels in type 2 diabetic patients with microalbuminuria in comparison with patients without albuminuria. Result with microalbuminuria (case) and 40 patients without microalbuminuria (control) participated in the study. Mean (CI 95%) urinary copper levels were 36.14 (14.54-57.74) and 14.77µcg /L (10.17-19.37) in the case and control groups respectively (P = no significant effect of diabetes duration or HbA1c on urinary copper. Conclusion: The present study shows diabetic patients with microalbuminuria have increased urinary copper excretion, however does not exclude the potential toxic effects of this high copper excretion on the progression of diabetic nephropathy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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