Gonadotrophin response to LH-RH in boys with delayed growth and adolescence.

Autor: SAVAGE, M. O., PREECE, M. A., CAMERON, N., JONES, J., THEINTZ, G., PENFOLD, J. L., TANNER, J. M.
Zdroj: Archives of Disease in Childhood; Jul1981, Vol. 56 Issue 7, p552-556, 5p
Abstrakt: Plasma luteinising hormone (LH) and follicle-stimulating hormone (FSH) concentrations were measured before and after intravenous luteinising hormone-releasing hormone (LH-RH) in 33 boys with growth delay. Eighteen were prepubertal and 15 pubertal. Basal LH and FSH levels were low in both groups with mean increments after LH-RH of 3.2 +/- 0.8 U/l (mean +/- SEM) and 2.6 +/- 0.4 U/l respectively in the prepubertal and 7.4 +/- 0.7 U/l and 2.0 +/- 0.3 U/l in the pubertal boys. The LH increment showed a positive correlation with increasing bone age (r = 0.71, P less than 0.001); FSH did not. The LH-RH response thus appeared normal in relation to the stage of maturity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index