Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities.

Autor: Corbin, Jackie D., Turko, Illarion V., Beasley, Alfreda, Francis, Sharron H.
Předmět:
Zdroj: European Journal of Biochemistry; May2000 Part 1, Vol. 267 Issue 9, p2760, 8p, 6 Graphs
Abstrakt: Examines the phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase. Identification of the binding sites; Mediation of cyclic nucleotide to regulate myriad physiological processes; Preincubation of the PDE5 in phosphorylation reaction mixture.
Databáze: Complementary Index