Triple selectin knockout (ELP-/-) mice fail to develop OVA-induced acute asthma phenotype.

Předmět:
Zdroj: Journal of Inflammation; 2011, Vol. 8 Issue 1, p19-32, 14p, 7 Diagrams, 6 Charts
Abstrakt: The article reports on a study conducted to assess the role of E-, L-, and P- selectins in preventing and treating the ovalbumin-induced allergic (OVA) asthma. It states mice were used to explore the collective role of E-, L-, and P- selectins in OVA-induced acute asthma phenotype. It states asthma phenotype was assessed by measuring pulmonary function, inflammation and OVA-specific serum IgE.
Databáze: Complementary Index