Immunoglobulin and complement deposition in skin of rheumatoid arthritis and systemic lupus erythematosus patients.

Autor:	Schroeter, A L, Conn, D L, Jordon, R E
Předmět:	IMMUNOGLOBULIN analysis COMPARATIVE studies COMPLEMENT (Immunology) FIBRIN RESEARCH methodology MEDICAL cooperation RESEARCH RHEUMATOID arthritis SKIN SYSTEMIC lupus erythematosus EVALUATION research
Zdroj:	Annals of the Rheumatic Diseases; Aug1976, Vol. 35 Issue 4, p321-326, 6p, 3 Black and White Photographs, 1 Chart
Abstrakt:	Rheumatoid arthritis (RA) was differentiated from systemic lupus erythematosus (SLE) by direct immunofluorescent techniques on skin specimens, using monospecific antisera for IgG, IgM, C3, C1q, properdin, and fibrin. Of 30 patients with RA studied, 20 had dermal vessel deposits of immunoglobulins and complement components in unaffected skin without the characteristic dermal-epidermal junctional fluorescence of SLE. Of 24 SLE patients studied, 24 had granular deposits of immunoglobulins and complement components in unaffected skin at the dermal-epidermal junction. [ABSTRACT FROM PUBLISHER]
Databáze:	Complementary Index
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