Autor: |
Szecsi, P B, Halgreen, H, Poulsen, S S, Axelsson, C K, Damkjaer-Nielsen, M, Kjaer, T, Foltmann, B |
Zdroj: |
Gut; Oct1987, Vol. 28 Issue 10, p1208-1214, 7p, 5 Black and White Photographs |
Abstrakt: |
Pancreatic tissue from 16 post mortem kidney donors have been examined for the content of pepsinogens. A zymogen with electrophoretic mobility, isoelectric point and molecular weight equal to that of pepsinogen C of gastric origin was found in all specimens. A comparison between pepsinogen C extracted from pancreatic tissue and gastric mucosa demonstrated immunological identity. Quantitative measurements with a radioimmunoassay showed pepsinogen C concentrations in pancreatic tissue three to 80 times higher than those of blood serum. Immunohistochemical staining gave positive reaction for pepsinogen C only in the alpha cells of the pancreatic islets. [ABSTRACT FROM PUBLISHER] |
Databáze: |
Complementary Index |
Externí odkaz: |
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