A prospective longitudinal study of depression, cognitive decline, and physical impairments in patients with Parkinson's disease.

Autor: Starkstein, S E, Mayberg, H S, Leiguarda, R, Preziosi, T J, Robinson, R G
Předmět:
Zdroj: Journal of Neurology, Neurosurgery & Psychiatry; May1992, Vol. 55 Issue 5, p377-382, 6p, 5 Charts
Abstrakt: A consecutive series of 105 patients with Parkinson's disease were examined for the presence of affective disorders, cognitive deficits, and impairments in activities of daily living (ADLs); 92 received the same evaluation 12 months after the initial examination. On the basis of the initial psychiatric findings, patients were divided into major, minor, and non-depressed groups. Patients with major depression showed a significantly greater cognitive decline, deterioration in ADLs, and further advance through the Hoehn and Yahr stages than patients with either minor depression or no depression. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index