| Autor: |
Kerr, Finlay, Ewing, David J., Irving, John B., Sudlow, Michael F., Kirby, Brian J., Kerr, F, Ewing, D J, Irving, J B, Sudlow, M F, Kirby, B J |
| Předmět: |
|
| Zdroj: |
Thorax; Nov1974, Vol. 29 Issue 6, p690-694, 5p |
| Abstrakt: |
, , 690-694. The respiratory effects of breathing with a positive expiratory pressure plateau (PEPP) was studied in 24 spontaneously breathing, alert, nonsedated patients with pulmonary oedema following myocardial infarction. When 20 patients breathed room air with PEPP a small rise in arterial oxygen tension (a) with a fall in alveolar to arterial oxygen gradient (A—a) occurred. Arterial carbon dioxide tension did not change significantly. When PEPP was used in six patients after breathing 100% oxygen for 20 minutes there was no significant change in a, A—a or anatomical shunt (Q/Q). Expired air collection in a further six of the patients demonstrated that although PEPP produced an increase in tidal volume (V), alveolar ventilation (V) fell slightly as a result of a decrease in respiratory rate, and oxygen consumption (V) did not change. In 10 normal subjects functional residual capacity (FRC), measured continuously in a whole-body volume displacement plethysmograph, decreased by a small amount when these subjects breathed with PEPP. Positive expiratory pressure plateau breathing in spontaneously breathing conscious patients with pulmonary oedema produced a small improvement in ventilation/perfusion matching not by an increase in FRC but by an increase in V. The increase in V probably altered the ventilation/perfusion relationships by a redistribution of inspired gas. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
