Is a persistent adenovirus infection involved in coeliac disease?

Autor: Carter, M J, Willcocks, M M, Mitchison, H C, Record, C O, Madeley, C R
Zdroj: Gut; Nov1989, Vol. 30 Issue 11, p1563-1567, 5p, 3 Black and White Photographs
Abstrakt: Recent evidence has implicated adenovirus 12 in the aetiology of coeliac disease so that persistent infection by this virus must be considered. We have undertaken a search for adenovirus DNA in duodenal biopsy samples from a total of 26 coeliac and non-coeliac patients. We could find no evidence of persistent virus DNA by Southern blot techniques even under conditions which approach a sensitivity of one copy of virus genome per cell, and use either adenovirus 12 or 41 DNA. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index