Sialic acids of human large bowel mucosa: o-acylated variants in normal and malignant states.

Autor: Rogers, C M, Cooke, K B, Filipe, M I
Zdroj: Gut; Jul1978, Vol. 19 Issue 7, p587-592, 6p, 2 Black and White Photographs, 1 Diagram, 1 Chart
Abstrakt: Five sialic acid variants have been demonstrated in normal, 'transitional', and tumour extracts of human large bowel mucosa by thin-layer chromatography. Two-dimensional thin-layer chromatography, with intermediate alkaline hydrolysis, confirmed that the variants were N-acetyl neuraminic acids with additional O-acylation. Cases studied so far show changes in the proportions of these variants in malignancy. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index